November 4, 2020

Creatine kinase

Creatine kinase

 (CK) is an enzyme found in the heart, brain, skeletal muscle, and other tissues. Increased amounts of CK are released into the blood when there is muscle damage. 1

When elevated CK levels are found in a blood sample, it usually means muscle is being destroyed by some abnormal process, such as a muscular dystrophy or inflammation. 2

CK catalyses the conversion of creatine and uses adenosine triphosphate to create phosphocreatine and adenosine diphosphate3

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age 4

  1. Creatine Kinase(CK) – Lab Tests Online – https://labtestsonline.org/tests/creatine-kinase-ck
  2. Muscular Dystrophy Association – https://www.mda.org/disease/distal-myopathies/diagnosis
  3. https://en.wikipedia.org/wiki/Creatine_kinase
  4. https://link.springer.com/article/10.1007/s00395-012-0276-2